Denis Mulleman Selected Research

Necrosis

1/2022	Infliximab Treatment Does Not Lead to Full TNF-α Inhibition: A Target-Mediated Drug Disposition Model.
7/2014	Relationship between inflammation and infliximab pharmacokinetics in rheumatoid arthritis.
1/2012	Influence of methotrexate on infliximab pharmacokinetics and pharmacodynamics in ankylosing spondylitis.

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Denis Mulleman Research Topics

Disease

21	Rheumatoid Arthritis 01/2022 - 01/2009
7	Ankylosing Spondylitis 01/2022 - 01/2009
3	Crohn Disease (Crohn's Disease) 01/2022 - 04/2006
3	Necrosis 01/2022 - 01/2012
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2021 - 01/2017
3	Rheumatic Diseases (Rheumatism) 01/2017 - 06/2011
3	Inflammation (Inflammations) 01/2017 - 06/2011
3	Sciatica (Sciatic Neuralgia) 12/2007 - 03/2006
3	Intervertebral Disc Displacement (Herniated Disc) 12/2007 - 03/2006
2	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2022 - 01/2020
2	Lipomatosis 01/2022 - 01/2006
2	Multiple Sclerosis 01/2017 - 01/2007
2	Osteoarthritis 05/2012 - 01/2007
2	Knee Osteoarthritis 05/2012 - 01/2007
2	Radiculopathy (Radiculopathy, Cervical) 08/2007 - 03/2006
2	Pain (Aches) 05/2006 - 03/2006
1	Musculoskeletal Diseases (Musculoskeletal Disease) 05/2022
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2022
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022
1	Neoplasms (Cancer) 01/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022
1	Axial Spondyloarthritis 01/2020
1	Rheumatic Fever (Acute Articular Rheumatism) 12/2019
1	Osteoporotic Fractures 11/2017
1	Liver Diseases (Liver Disease) 11/2017
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 06/2017
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2017
1	Infections 01/2017
1	Chronic Disease (Chronic Diseases) 10/2016
1	Ulcerative Colitis 10/2016
1	Psoriatic Arthritis 10/2016
1	Osteomyelitis 03/2015
1	Hip Osteoarthritis (Coxarthrosis) 03/2009
1	Uveitis 01/2009
1	Spondylarthropathies 01/2009
1	Intervertebral Disc Degeneration 01/2007
1	Acquired Immunodeficiency Syndrome (AIDS) 07/2006
1	Alcoholism (Alcohol Abuse) 07/2006
1	Tuberculosis (Tuberculoses) 07/2006
1	Neuralgia (Stump Neuralgia) 05/2006
1	Glucose Intolerance 01/2006
1	Low Back Pain (Lumbago) 01/2006
1	Discitis 01/2006
1	Weight Loss (Weight Reduction) 01/2006
1	POEMS Syndrome (Syndrome, POEMS) 01/2004

Drug/Important Bio-Agent (IBA)

13	Infliximab (Remicade)FDA Link 01/2022 - 04/2006
10	Monoclonal AntibodiesIBA 01/2022 - 04/2010
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 03/2006
6	Adalimumab (Humira)FDA Link 01/2020 - 01/2007
5	Pharmaceutical PreparationsIBA 05/2022 - 03/2012
5	Biological ProductsIBA 05/2022 - 01/2006
5	Rituximab (Mabthera)FDA Link 01/2022 - 10/2016
5	Methotrexate (Mexate)FDA LinkGeneric 01/2020 - 11/2009
4	AntibodiesIBA 01/2020 - 06/2011
3	Tumor Necrosis Factor InhibitorsIBA 11/2021 - 01/2009
3	Biomarkers (Surrogate Marker)IBA 10/2016 - 06/2011
2	GlucocorticoidsIBA 01/2017 - 07/2006
2	Hyaluronic Acid (Hyaluronan)IBA 05/2012 - 03/2009
1	AntigensIBA 01/2022
1	tocilizumab (atlizumab)FDA Link 01/2020
1	Certolizumab Pegol FDA Link 01/2020
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2020
1	AdiponectinIBA 01/2020
1	Immunosuppressive Agents (Immunosuppressants)IBA 06/2017
1	SteroidsIBA 06/2017
1	Immunoglobulin G (IgG)IBA 01/2017
1	CD20 AntigensIBA 10/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2015
1	C-Reactive ProteinIBA 01/2009
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2007
1	Interleukin-1 (Interleukin 1)IBA 01/2007
1	Glucose (Dextrose)FDA LinkGeneric 01/2006
1	Silver Sulfadiazine (SSD)FDA LinkGeneric 01/2006
1	Immunoglobulin A (IgA)IBA 01/2004

Therapy/Procedure

3	Therapeutics 01/2009 - 05/2006
1	Aftercare (After-Treatment) 01/2022
1	Transplantation 11/2017
1	Liver Transplantation 11/2017
1	Retreatment 10/2016
1	Duration of Therapy 03/2015
1	Intra-Articular Injections 05/2012
1	Lasers (Laser) 08/2007
1	Decompression 08/2007
1	Conservative Treatment 03/2006
1	Caloric Restriction 01/2006